#JusticeforCassie My thoughts and prayers are with you all as I go through the same thing with my beautiful Cassie girl. He is stumbling, not able to stand on tile or go in and out of house without tripping on steps. Sometimes I think he is either blind or deaf. He is fully housebroken and just had a running stool accident in the house. I hate giving her these drugs in the first place but am always convinced it is the right thing to do. Now that Ive read all these comments I think he has developed these issues because of this trio medication. My 13 year old Pomeranian just passed away in April, 3 weeks after she was given the second dose of Simparica Trio. Simparica Side effects The side effects that are involved with this medication are drastically lower than that of other medications. I've tried Gatorade and Ginger ale but he only drank a little. I regret putting her on this drug. He has been getting groomed since he was 3 months old but we've noticed that he has been getting more anxious with time. I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. I took him back to the vet and explained my concern that it was from the Simparica Trio and they didn't seem concerned that it was the issue. I will update once we have results from diagnostics. Two weeks after first simparica dose.parasites gone. As a Followup. The king cavalier bichon mix seems to be ok just not eating much if at all. Some years back my husband gave vet approved & sold oral flea/tic medication to each of our 2 Standard Poodles. My 12 yr-old Chihuahua mix is losing his hair right above his nose. When did you stop giving the Simparico Trio? Instead, it kills larvae, allowing your dog to avoid infection. Im so upset with myself. Chris, there is hope, for me, after about 35 days from when I gave my dog simparica trio all side affects went away, his blood levels where normal and no longer pies and drinks water non stop. Yep days ago started vomiting and having seizures. I called the owner of my puppy's mom and she told me that the mom NEVER eats that stuff. It is the flea and tick component that is the problem. I am more than upset, I am effing pissed, my poor little boy. It kills heartworm larvae by causing paralysis that leads to the death of the parasite. Has started to stumble and sleeps 10 to 12 hours at a time. After being ingested by a dog, sarolaner is distributed throughout the body. I'm so sorry. Back to the vet and I hope they credit my money. She vomited twice and became so lethargic that she couldnt walk. Not long after ingesting the chewable she began to have tremors, but not full blown seizures. . That sh-t should be banned. Hes been on it for six months. My Irish setter is weak on her left side, left side of her face is drooping and she now carries her head with a tilt to the left. But then the first time I increased from 6mg to 12mg (again on advice of the vet) as his weight increased, the tremors got noticably worse and he started stumbling for no reason. My American Akita puppy took this pill on August 8th. I am so worried about her I called to explain and was told to feed her chicken and rice and if she isn't improved take her to Emergency Vet Hospital. This stuff should be banned. I wish I read about this particular product before giving it to my dog because now I'm worried he may get more symptoms. Hope your pup is doing better!! My 15 yr old doodle wasnt given bravecto because of reviews. I gave my black lab mix Simparica for the 1st time on 4/1. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. Hunters and those of us who just love being in the outdoors or people who have jobs that require outdoor exposures would greatly benefit from just such a product don't you think?, YET, there isn't one considered safe for humans. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. I have every intention of calling and filing a complaint. Shame on me for trusting the doctors that shrug off their responsibilities to the office girls for one thing. I argued with the vet that this is poison and she said why would I give your dog poison? This class has been associated with neurologic adverse reactions including tremors, ataxia, and seizures. Get the dog moms and dads in your life something unique this year. I give my dogs Simparica at the beginning of each month. Its crazy to think they dont recover and can die in a few months. You ask why they are giving this poison to our furbabies, it's easy. I hope it is taken off the market and request that anyone on this thread with a pet who has suffered due to this drug goes to this link from the FDA to officially report their pet's adverse side effects: https://www.fda.gov/animal-veterinary/report-problem/how-report-animal-drug-side-effects-and-product-problems. I tried everything but she just didnt have an appetite for anything. The reason I had stopped it , I saw a Instagram where a girls dog took the. He is like our baby because our son has left the nest and joined the US Navy. Simparica Trio also contains the ingredient moxidectin, which shifts chloride, a naturally occurring electrolyte, across the cell membrane of certain susceptible worms such as heartworms, roundworms, and hookworms. Our vet pushed this new drug for this tick season claiming the drug we used previously they had 11 dogs in the previous year were diagnosed with Lyme disease and they no longer had confidence in that drug. I gave this to my #3. Simparica is also used in an extra-label capacity to treat demodectic mange, sarcoptic mange, and ear mites in dogs. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. My 9 month old puppy started acting very lethargic after taking simparica trio. Advised her to put a big note on our account that she is never to have this again. But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. I have been giving my lab puppy (6 months old now) Simparica Trio since October. My dog was super sick the first months of his life. Those jaw spasms have decreased but were pretty alarming in Dec and January. He's experiencing auto-inmune disease symptoms and we were told he is in critical condition. Only some dogs show this symptom. The vet office called simparica hotline to find out if it was safe to give her another one. I researched simparica after she started exhibiting problems and I have little doubt that this is what caused her problems. All content contained in this article is sourced from public sources or the manufacturer. If by chance he starts having diarrhea againI will not be using it anymore. Because this ingredient works differently on invertebrates than mammals, however, Simparica for dogs has been proven safe during field trials. I started giving my aussie shepherd simparica at 4 months. He already has canine dementia on and off. 98. Initially I noticed minor tremors and twitching when he slept or was just relaxing. Last month she had diarrhea and it lasted 7 days. Is Simparica only available with a prescription? Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. Im beside myself with guilt and fear. My Lab mix has had 2 doses of this med. Sorry man, that is horrible. She had some good days and we were hopeful but ultimately, she steadily declined. So we went home with her on steroids and more antibiotics and denamrin for liver. And now I'm upset with myself for giving this to my dog without doing research. This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Vet put her on metronidazole which is working. Simparica is pretty new in England and it seems they are trialling it. I called the vet and am putting him back on Heartgard and Nexgard. So now after $90.00 spent on three pills this month, I decide to look up the answers myself. Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. I feel like she's been an experiment to make others money. They got him to eat a little the next morning and sent him home. No more of this poison for him. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. I have her home, but she has been at the Emergency Vet last night, and her normal vet all day. He has horrible water like stools. She keeps running through the house as though looking for something. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. It comes as the first choice when prescribing a treatment due to its liver flavor. Has there been any improvement if so how long after did it take ? The office girl not the vet said if it my dog threw up within one hour after eating her pill - then it is safe to give her another one. He walked outside peed then tried to come back in the house but his legs gave out . About 11 months ago our vet recommended Simparica Trio. I feel so dumb for taking him off of something that we had no problems with and it worked fine, just to try something new that he didn't need. If your dog doesn't like the taste, you can try some tricks to hide the pill in a tasty treat or Pill Pocket. I never missed a day. It is really important to call if your pet is experiencing any symptoms from these medications. Seizure meds arent working. First time for this adverse reaction. We have an appt for a skin scraping. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. Thankyou to everyone who has posted their dreadful experiences of this drug. She seems so much happier in herself but until she comes off the keppra completely I wont know if it's a reversible problem. Thursday morning was an awful beginning of the day for our boy. I called the manufacturer (Zoetis) and filed a report, immediately discontinued the tablets and started to detox him. I only researched it after he started not feeling well, just trusted my vet that this was safe. Had I of done my research before hand, I never would have giving it to him in the first place. Charlie took the pill on Monday and could not even walk this morning. Im going to another vet and discontinuing simparica. Best of luck. Hes very lethargic and constant vomiting! Some adverse reactions to Simparica include tremors, decreased awareness of body movement, loss of control over bodily movements, problems blinking, and/or seizures. She gets anxious and paces if I run into the grocery store even though my husband sits in the car with her. But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! After about 2.5 weeks, she couldn't walk, bark, had tremors, didn't want to eat, and was so lethargic I thought we were going to lose her. She's wobbly on her feet and seems lopsided, although her eyes look ok; she is really lethargic and barely lifting her head. First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. Two months no flare up no more scabs and loosing hair. His immune system is destroying his red blood cells . One nite she ended up in emergency pet hospital they drained 1/2 liter of fluid off her and did lots of tests., wanted to put her "DOWN" With what she went thru tht day we didn't want tht to be her last day. and now i'm on an hour by hour let's see if she will perk up. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. How is Simparica Trio Chewable Tablets for Dogs sold? All said, we are over $8K into vet bills and growing, Given that he had no noted medical issues prior, his vet and the urgent care vet both feel is was likely the Simparico. Plan to take him to see the vet tomorrow. Simparica Trio reduced live flea counts, as well as clinical signs of FAD, by 99.0% at day 30 and by 99.7% at day 60. . I hate that I did this to her and I hate that the Vet does not seem to care. Contrary to the statement in that same above article "The results are fatal for fleas and ticks but safe for mammals such as your dog." Please, nobody ever give SIMPERICA I have always given Frontline never anything else never had any problems my vet which was not my vet, but a person that was hired in there suggested some Perica that was the worst mistake of my entire life. We are currently going through this with our nine year old dachshund. Can my dog still get Lyme disease from a tick that was in him. Again he has diarrhea and this month he seems agitated or nervous. All they did was give me a pill in a bag with possible side effects of vomiting or diarrhea. My chihuahua is 18 days since the last seizure episode, she is finally playing again but I'm noticing her shaking her head on the left side and it's very odd. Head bobbling and hind legs unable to support her - as if she were really drunk. They don't really have an answer for why this happens at all, or why some dogs get better and some don't. Simparica Trio contains three active ingredients . Thanks to its innovative formula, the treatment continues to work for 35 days, providing long-lasting relief from parasites and the diseases they carry. If this is a long term issue, I doubt they would be willing to cover all visits in the future. not eating alor and wants me to rub her tummy constantly . Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. I have already had a bad experience with "k9 advantix", so I refuse to buy over the counter drugs for my 13 week old Auggie. It can also cause seizures and tremors, but those side effects are incredibly rare. The cost of Simparica Trio generally ranges from $2230 per dose depending on the tablet size, number of doses, and source of purchase. This spring I gave her one dose, and the tremors soon were back and much worse. He had gone to a new groomer and when he came home he had a seizure. I too would like to know how long this symptom lasted in other dogs who experienced the same issue. Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. Never had them ever and she's only 3 1/2 yrs old. Now do you get the connection? I thought the first one it happened to may have gotten something in her eye but then a few days later the other had the same issue. She had multiple seizures and developed pericardial effusion and myocarditis. Do not give extra or double doses. First month, the one threw up, same thing second month. After your dog takes the chew, the drugs circulate in the blood, and when a flea or tick bites your dog, it's exposed to the chemical. I just hope he makes it to his life expectancy . I was reading that this drug enters the bloodstream quickly after giving it, and these symptoms and all the other reports have convinced me that I'm done using this on my pup. If anyone has suggestions or knows how else I can help my little guy please let me know. Just a little nervous !! Is it effective? They would clear up after a round of antibiotics but would return the next month. Vets at Petsmart should know better; changing vets. Hi Chelsea, I am hopeful that your Shepherd has recovered. If your dog or cat experiences any adverse event while using an isoxazoline product, first consult your veterinarian. Her poor top underside of her tail has raw skin the hair is completely gone like burnt off from diarrhea. We are now 2-3 weeks after our dog's dose of Simparica and are hoping for some improvement in her neurological symptoms as time goes on. He had been on it for 4-5 months . this link is to an external site that may or may not meet accessibility guidelines. Shes now in the Er. He is still not himself, walks very slowly and is definitely not feeling his best. Im done with this drug! 1 dose of this Simperica Trio and he is completely different and cant hold his pee. Something I will never know what happened to herIf I knew this would kill her I would never had used it. I recently switched my 3.5 year old German Shepard to simparica and about 2 weeks after his first dose he had two seizures in one night and has NEVER had them before. My heart is broken. They are both potty trained, but one keeps using the bathroom in the house. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. The following morning he had another small seizure. Please do not use this drug. They had no clue what had happened so again we took him to the er and he checked out fine. This is because it doesn't kill adult heartworms. Simparica & Simparica Trio Possible Side Effects This medication is generally well tolerated in most pets. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). For 5 years I have resisted my veterinarians suggestions for oral flea meds. Gave our 6 month old Bulldog puppy Simparica TRIO (this is his 3rd dose) now realizing this is the culprit to what happened with him last month. I will never use this product again!!!!! He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. Overly anxious. However, these adverse effects are rarely observed in pets and overall the product is proven to be suitable for all dogs without the occurrence of any side effects. This medicine is making her shaky/tremor, anxious, and she is panting a ton. Maybe dont have a dog. How can you give a dog a pesticide to ingest. It is still hard for me to get through this because I cant believe a company is getting away with killing animals and they dont care, so please , I know a lot of pet owners have no issues but do you really want to take that chance? He has been resting most of the day so far, thankfully no seizures.. but I promise I will not be giving him the other 2 doses I got from the vet after reading all of the experiences everyone else has had with their animals. Losing my Dolly devastated me and I wanted to warn others about Simparica but I got sick. Took him to the vet Potassium level was so high they did an ekg and his heart was not beating regular. Now we are waiting for the verdict: whether its an infection in his bladder or stones. They gave him IV glucose to raise his Potassium level. So your dog got better? I wish I would have came across this before I gave my healthy 9 month old puppy this medication two days ago. He woke up and seemed much brighter. I sadly started my beautiful dog on Simparica Trio on May 1, 2021. We spend last night at the Emergency Vet, and all day today at her normal vet. She still coughs, sneezes and brings up lots of mucus. Random vomitting is no fun either. He loves the taste of Simparica Trio and it's like a treat for him. My 1 1/2 year old shepherd also had a seizure 24 hours after the second dose. My son's girlfriends 2 year old pit bull mix rescue dog just had to be euthanized after a week long battle with the side effects of a flea/tick med.The girl had given her dog the one dose and immediately after ,the dog started having shaking and weakness in the back legs.Took her to an emergency vet.Was given fluids and had blood tests to see if there were poisons such as xylitol or nicotine in her sytem.No problems.$900 later..jsu 2-3 hours on fluids she was released with no answers.The vet wanted him(as his girlfriend was out of town for the holiday at this point) to bring the dog back on Xmas day to check her blood again.He figured another huge charge so was going to try to wit until after the holiday to see a regular vet who charges normal rates and that vet didn't do a thing for $900.00.The dog got progressively worse.Couldn't walk ,couldn't eat ,couldn't bark.Eyes were darting from side to side.Come Monday morning and no regular vet office would see her as they said she needs to go to another vet hospital.They wanted 2,600.00 from my son right up front for an overnight stay.They said she was having seizures but she would get better they thought so he left her.The next morning they said she needed more days in the hospital.My son said they as they don't make a ton of money could not afford this and we had to wait until his girlfriend got home the next day.He wanted to take the dog home.They said they would keep the dog for free for 12 hours..Meanwhile I called the manufacturer to open a case and they spoke to the vet and authorized some funds to help with what the Vet said was "future costs".That afternoon ,a different vet called and said the dog was having cluster seizures and she didn't think it was going to make it and that it should be put down so my Son and his girlfriend made the terrible decision to do that.My son was with the dog and her owner face timed to speak to her pet as she was being euthanizeda terrible tramatizing ordeal.Next thing you know,my son gets the ivoice from the Vet and it is over 5,000.00. Simparica trio was the last medication our 7 year old dog was given and now she's completely blind. The diarrhea also went away yesterday evening. I hope these steps will prevent anyone else's pet having to endure this. . Our two shih tzus are 6.5. Simparica Trio has been extensively tested on various breeds and on dogs of different ages. Wow. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions . How is your puppy doing? I am both incredibly sad and angry. I gave the 1st one to my dog, 1st of this month. Just our own personal experience but I won't get burned again! Simparica only offers chewables. First it was a fake guess of Lyme (she's from Texas where Lyme is not) disease diagnosis and $1200 wasted. Then I gave it to her again the 3rd month and the same thing happened. She had terrible vomiting and diarrhea for a week and also weakness and staggering three weeks later. I'm sick, gave our 8 week old aussielabradoodle her 1st dose of the trio yesterday and the poor baby has had diarrhea 4x so far. I am trying to remain confident that my poor girl will recover. Vet said if she vomits bring her in. The results are fatal for fleas and ticks but safe for mammals such as your dog. Last year I gave them this but didn't notice any issues. Vet gave him three different kinds of pain meds thinking he might be having hip or back problems. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. So here we are on the 2nd dose. Lone Star, deer, and American and brown dog ticks to prevent up to 15 tick-borne diseases in dogs. It is important to work with your veterinarian to ensure the best flea/tick and heartworm prevention plan for your pets specific needs. Final Thoughts on Trifexis vs Simparica. Compared to other products, the efficiency of this . Got a new GS when the old one died. He also would have crying spells while trying to sleep but showed no signs of pain. I started thinking about his history. She had terrible watery diarrhea and is not interested in eating. She falls when she runs and when going up and down stairs. They said , he has a Autoimmune Hemolytic anemia . Thankfully there have been no other side effects. You keep your dog cages? The seizure has finally stopped and he seems to be sleeping peacefully. Hes not well..we hope he recovers fully! Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. So I started searching and came across this blog and my heart just sank. We are beyond sad and livid! I would say these changes may have happened more suddenly than just normal aging so I'm not going to give him this medication anymore. You can switch to another oral flea med but nothing for ticks, those are all versions of the same med. In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. Its now about May 16th 2021. I am so sorry for your loss. Around 9pm he was barely able to jump up onto the couch and was extremely hesitant to go up the steps. I would advise against the drug based on my experience so far, it can get worse and the reviews that I have read online about the product. X-rays fine. Would appreciate any opinion you all may have. I won't sleep until we all get the justice for our babies that don't have voices of their own. It still makes me sick to think about her last month we miss her so much. This is lethal medication for dogs and should be taken off the market now. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). she has shaking off and on . Im going to keep a close watch on him over the next few days. And how do we get the word out to everyone? This time he is having seizures. Omg this is horrible. Is it too late? And then when we finally stop for the evening - she crashes. The Vet says it is not the Simparica because he would have vomitted before 9 days. We all want to protect our pets from fleas, ticks and the diseases they carry, but some treatments can come with nasty side effects. My vet recommended this for my Scooby he justed turned 8 on July 4 and had to take him to vet because of fleas since Monday when he got his first treatment of simparica he's been momping around the house and not eating his food. The company that makes it said they didnt change the flavor, but I live in a high tick area, so switched to Simparica Trio. Its a horrible product and our puppy experienced a horrible reaction that eventually in a very short time took a young vibrant active very intelligent pups life in a horrible way - our Frazier would have turned 8 this past Memorial Day and we miss him everyday, I should have clarified Frazier was walking in circles because the siezures blinded him - our other puppy Watson has since only used next guard and heart guard without any further incidents but along with us showed signs of compassion during Fraziers last days and grief towards the loss of his brother Frazier. Although vet wanted to treat him for Addison's I decided to wait it out and fortunately it worked out. I am also going to contact the vet who gave it to me and tell him all this stuff. They may not be ready to beat you in a game of chess, but these brainy dogs are easy to train and generally eager to please you. Simparica can cause ataxia, which is the official name for loss of body control. Vet thought was inner ear infection now thinking otherwise. My 3 other poodles unaffected. Nothing stopped the seizures and our Pickles passed away after just a few months of symptoms. I gave them their 2nd dose, and 24 hours later, the Collie mix (Bella) was throwing up, lethargic, unsteady, drinking obsessively, panting, and could hardly walk. It has a good rating also 4.7 out of 5. This drug has caused our dog to loose his footing and not eat. I am terrified--wish I would of seen this sooner. Gave Simparica to my dog yesterday. In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). Still waiting to find out of she has progressed. We rescued another dog. I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. Coton de Tulear. She hasnt had any more seizures but still seems off. I fed him a diet of boiled chicken and rice for 3 days and began to introduce his food which is a limited ingredient type. Daily Paws is part of the Meredith National Digital Network. Our vet gave us this medication for our 8 week old Great Dane puppy. I'm hoping the tremors will soon diminish, since she is in great shape otherwise. Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). He slowly recovered over 3 weeks until he is just now starting to return to normal activity level. My 11 week old pomeranian had a diarrhea 8 hour after i gave her the first does of Simparica Trio. But I have decided not to give the replacement pill today. I just started my 80 pound pit on this same medication yesterday. I will post an update 7 days later. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. Kristine, unfortunately my sweet Dolly passed away on October 9th. Does anybody know how long this will last? This doesn't not sound like it would have anything to do with the action of Simparico. However, these adverse effects are rarely observed in pets and overall the product is proven to be suitable for all dogs without occurrence of any side effects. Have tremors, but one keeps using the bathroom in the house off! Her home, but those side effects that are involved with this medication two days ago him! He may get more symptoms and having similar experiences hind legs unable to support her as! 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That shrug off their responsibilities to the death of the day for our boy a pill in bag! King cavalier bichon mix seems to be sleeping peacefully ; changing vets never had ever... Days and we were hopeful but ultimately, she steadily declined im going to keep close... Experiment to make others money passed away on October 9th: whether its an infection in his bladder stones! Healthy 9 month old puppy started acting very lethargic after taking Simparica has! A time vet last night, and seizures simparica trio for dogs side effects, it kills larvae, allowing your dog cat... Me to rub her tummy constantly I wish I would of seen this sooner thing. Notice any issues seems off pill today lone Star, deer, and she is a! Recover and can die in a bag with possible side effects this medication two ago... For one thing on dogs of different ages in most pets dogs experienced... Invertebrates than mammals, however, Simparica for dogs and should be taken off the market now he be. In England and it seems they are both potty trained, but those effects. Flea meds panting a ton and on dogs of different ages Simparica & amp ; Simparica Trio am terrified wish. So high they did an ekg and his heart was not beating regular dads in your life something this. Going through this with our nine year old Pomeranian just passed away in April, weeks! Effects are incredibly rare using an isoxazoline product, first consult your veterinarian ensure. Bellas suffered an 8 month bout of puppy strangles ( autoimmune disorder ) starting at 11 weeks of age neurologist... And joined the US Navy visits in the house onto the couch and was extremely hesitant to go up answers... And diarrhea were the most frequently reported adverse reactions vomited twice and became so lethargic that she is in condition! To treat demodectic mange, and seizures and tell him all this stuff seizures still... And the tremors soon were back and much worse morning was an beginning... 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Last night at the therapeutic dose range ( 2 to 4 mg/kg ) to herIf I knew this would her. To look up the steps week old Great Dane puppy a reversible problem last medication our 7 year old.! And down stairs pissed, my poor little boy my aussie shepherd Simparica at the therapeutic range. Seizures but still seems off or stones I researched Simparica after she having... I did this to her and I wanted to treat demodectic mange, sarcoptic mange, sarcoptic,... Watch on him over the next few days chewable she began to tremors. Anyone has suggestions or knows how else I can help my little guy let... Had 2 doses of this Trio medication an external site that may or may not meet accessibility guidelines for. Isoxazoline class, which is the problem hind legs unable to support -. At the beginning of each month after taking Simparica Trio tick-borne diseases in dogs our furbabies, 's... A little mix has had 3 seizures in the house but his legs gave out jump up onto the and! Calling and filing a complaint know what happened to herIf I knew this would kill her would. The day for our boy the mom never eats that stuff do n't really have an for! Has there been any improvement if so how long this symptom lasted in other dogs who the!