SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. ( I had to get a different vet for my pup because my current vet couldnt get him in to start his vacines for 2.5 months. The tail curling and pacing lasted over a week. Id like to have a Smooth Collie in the future. Your thoughts? Any dog can have a sensitivity to a certain substance and should always be monitored for reactions after a new product has been administered. Any thoughts on either of these? Simparica TRIO Chews for Dogs 44-88 lbs (20.1-40 kg) - Green 6 Chews (11/2024 Expiry) Was: $115.99. Advantage takes care of fleas at all life stages and is even supposed to kill them on contact, and it also covers lice. Thanks much for the info before I bought anything! A couple people claimed that the trick to getting them to work well is to use a slicker brush to part the fur of the mane, to ensure the collar is close to the skin for best effect. They both have tolerated Bravecto very well.no noticeable side effects. Their lower cost makes them appealing for those of us living life on a budget, but its worth it to spend just a little more for your canines safety. Great summary! It seems unlikely for that much time to elapse before a reaction, but I would definitely consult with a veterinarian. So tick protection is also a must for us. So heres the culmination of my research: information gathered from laboratory case studies, veterinarians, and Collie owners, breeders, and exhibitors. Options: 3 flavors. If youre going the oral tablet route, Credelio is one I personally feel comfortable with! (No judgment if you didnt see that section: I know its a very long article and I expect most people are looking for a quick or specific answer and dont actually read the whole thing ?.) (I have to give them baths with a very mild or medicated shampoo.) Our vet who really pushes natural (Chinese) medicine for pets, recommended Bravecto for our collies after the Seresto collars were simply not working for Roxie (6 ticks in 2 months even with trying a second Seresto collar thinking the first one might be defective). She has always had a sensitive stomach, but as she gets older, it gets worse. Interceptor was also recommended by my entire local Collie Club, including Pati Merrill, the retired former president of the Collie Health Foundation. And its possible for dogs and humans both to have allergies even to natural essential oils. Altogether, the agency received 75,000 incident reports, the majority of which were complaints of skin reactions in both animals and humans. I went back and edited my comment for consistency. We will get her in about 3 weeks. The spray can also be applied to your dogs bedding for a boost in pest prevention and an improvement in smell. Matching game, word search puzzle, and hangman also available. If the topical treatment (the shampoo) contains some form of -mectin, that could cause a sort of overdose if given in conjunction with Heartgard, which contains Ivermectin. Observaciones clnicas de salud, Parmetros toma de muestras sanguneas para medidos farmacocintica. Second, Id like to ask a question if you dont mind. Simparica TRIOse administra va oral una vez al mes, a una dosis de 1.2 mg de sarolaner/kg de peso corporal; . Fleas can lay up to 1300 eggs within 50 days, 4 but Simparica Trio kills them before they can even lay eggs. We have two collies, Dash (8 yr old male) and Roxie (2.5 yr old female). Could that have been the cause of the seizure, even though she took it more than a month ago? It has the same active ingredients as Seresto (plus one), so a bit stronger. The author states this had no connection to the drug study. Capstar can be used with heartworm products and some other flea products (see link above for compatibility chart), and it can be given to pregnant or nursing dogs and cats, and even puppies or kittens that are older than 4 weeks or heavier than 2 pounds. For dogs who have a case of mange or ear mites, the treatment can involve topical applications of compounds containing (you guessed it) Ivermectin. I gave a mini aussie and a minnie aussie/border collie mix. At least once a week or before we go walking down woodland trails, I also take the precaution to spray my dogs legs and lower body (and my shoes) with Natures Best or Natural Chemistry flea and tick repellent. I was bummed to read its the safest since I dont want him to have it every again (a little off balance shortly after and salivating) but later he had an episode with fixed eyes, stuck in a strange position, stiff muscles, blind, he had a heart rate half of what it should have been and a head tremor. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. Thank you for writing this article. My vet wants to give him a vaccine (?) The amped-up version, Interceptor Plus, also contains praziquantel, which is used to treat tapeworms. Simparica Trio is well tolerated in dogs with a deficient multidrugresistance- protein 1 (MDR1 -/-) following single oral administration at 3 times the recommended dose 1 THE SIMPARICA TRIO RANGE INCREASING COMPLIANCE FROM 2 MONTHS PER YEAR TO 12 WITH VETPOST COULD INCREASE REVENUE BY 600% Trish. Its in lots of grain-based foods because lots of grains are stored with diatomaceous earth to keep the bugs from eating the grain.. The study also established safety: Simparica Trio was well tolerated by the dogs, even in the presence of concomitant medications, with adverse effects mild and minimally occurring. I tried it on both my Collies, for example, and it made them so itchy that I had to give them a bath after a day. (Most vets are going to recommend to you the products they carry in stock, but you can order online from Chewy or pet pharmacies.) Two dogs were positive for D. immitis antigen but not MF on days 210 and 236. It comes in pill form, starts working within 30 minutes, and will kill all the fleas on a dog within 4 hours. Do you have any recommedations about Simple Guard3 for Shetland Sheepdogs? Simaprica Trio is a multi-spectral treatment for dogs that treats external pests and infectious internal parasites. Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. Safety has not been evaluated in pregnant, breeding or lactating dogs. But I do think K9 Advantix is a good choice for Collies who arent overly sensitive. Zoetis (Simparica, Revolution Plus): 888-963-8471; If you prefer to report directly to the FDA, . (I didnt find the information about the 6 reported seizures until after I had already given it to my dogs and seen no ill effects from it.) I appreciate your help as I was trying to navigate so much conflicting information!! I interviewed a few people (rescue workers, owners, and breeders) from that group for this article I wrote about Border Collies. Fleas were treated with effifax, active ingredient fipronil. I appreciate the research in this thank you! I do think that Sentinel Spectrum is the safer choice, though the downside is that its less effective. I understand that most dogs are not having negative side effects as a result of using Bravecto, Nexgard, or Simparica but enough dogs are. This product is an awesome all in one, monthly chewable tablet. My personal vet is knowledgeable of the MDR1 gene mutation (now also referred to as the ABCB1 mutation), and he recommended Interceptor to me for my mutant/normal Collies. Substantially improves the clinical signs of Flea Allergy Dermatitis in dogs. K9 Advantix II Flea, Tick and Mosquito Prevention for Dogs, 6 Doses. In their emaciated and poor health state, AND being border collies, I was afraid I would overdose or poison them giving both drugs. Submit a story, ask a question, or just say hi; Emily would love to hear from you. tratados. Dogs with the MDR1 mutation can be 200 times more sensitive to the drugs than dogs that do not have this mutation. No one knows yet why some dogs react to isoxazolines like Simparica and others dont, and theres no way to know until its tested on an animal. ? Revolution and Stronghold even tested safe over the recommended monthly dosage for dogs with the MDR1 gene, and they hold the distinction of being the only heartworm meds that did not produce any negative drug reactions. Ive talked to Collie and Aussie owners who absolutely swear by their Seresto collars and others who are livid because they made their dogs neck bald! Dogs with normal MDR1 genes can usually tolerate oral dosages as high as 2,500 mcg/kg of body weight before signs of toxicity are seen, while dogs with two copies of the defective MDR1 gene can tolerate only up to 100 mcg/kg of oral ivermectin. Will you be updating this article with regard to Seresto? My Collie is double MDR1 mutant. All dogs treated with SIMPARICA TRIO were negative for D. immitis antigen and blood microfilariae at study completion on day 330. Excellent research and well written article! a thorough study conducted on MDR1-affected dogs, this study conducted on twenty MDR1-affected Collies, the Washington State University of Veterinary Medicine, safe for use with anthelmintics like heartworm meds, Some swear by food grade DE (diatomaceous earth) as a natural dewormer. I know Simparica is more convenient since it means giving one monthly preventive instead of two, but the trade-off with the combo meds is that theyre usually stronger. Last time I took my Collies to a pet store here in parasite-infested Florida, I asked one of the clerks what they sold the most of as far as flea and tick preventives. Though not meant for long-term treatment, it is excellent for short-term intervention in the case of severe infestations or for a dog who happened to pick up a few fleas on an outdoor ramble and is in need of some quick relief. Selamectin is their shared main ingredient. I disagree. Maybe regular Interceptor would be fine since it doesnt contain Praziquantel, but its difficult to say exactly what your dog is reacting to. I had started my GSD on Revolution, but really always liked Frontline better and since that seems to cover more ticks and still protect us from unwanted mites I probably will lean toward that. No treatment-related clinical signs were observed. From the standpoint of MDR1 dogs, it is safe. Thanks Emily! Bear with me for a little pharmaceutical science, which I promise is important and will make sense in the end! I dont use Credelio anymore and just stick to Frontline Plus combined with a weekly application of Natural Chemistry flea and tick spray. In FL resistance is bad, and we split our time between FL & NJ. Some dogs will even react to Pyriproxifen (one of mine has), so just be prepared to bathe and scrub if there any negative reactions like skin redness or excessive scratching after application. As long as I remember to apply it at least once weekly, Ive found it to be very effective. They said Frontline Plus doesnt really work anymore like it used too. After a single administration of 5 times the maximum recommended dose to this sensitive dog breed, transient Dinotefuran in particular is a strong pesticide, and all 3 of those ingredients combined are harsh on sensitive skin. It is supposed to repel mosquitoes as well but I am very nervous about not using a heart worm preventative. So far, noone has the answer to this seemingly-simple question as to what ticks their product actually acts against. All Rights Reserved. We gave her the first dose in late February and there were no adverse side effects for Sugar. Theyre so fun and exciting (and sometimes exhausting) at that age , What about the use of Simperica Trio for a Collie. I have to tell you that I am no expert, but I would feel the same and be wary of giving Interceptor Plus again. The benefits of Simparica. As far as I know, Frontline Plus is still safe to use, but as with any chemical product theres always a risk! Dogs, 6 Month Supply removed from the wishlist. Sarolaner had been approved in 2016 to treat flea and ticks, moxidectin . If you have more than one dog and they engage in mutual grooming, you should probably pick a different parasite preventive. However, it does claim to kill fleas on contact. I am going to try WonderCide as recommended by my Vet for fleas. Thank you for the warning. Unless youre, say, an expat living in China, you can definitely find a better option. But of course, do talk to your vet and see what they know. In summary, it looks like Parastar Plus is comparatively a gentler product than some topicals since the concentrations of its active ingredients are fairly low, but the trade-off may be that it lacks the strength of products like K9 Advantix II. He was getting quite stiff and sore, but he acts like a much younger dog now. I have two beautiful rough collies & of course always want to keep them safe. Now: $92.79. (My dogs dont groom each other or really play that way now that theyre older and settled, so I feel comfortable using topicals now.) Heres a personal anecdote: for years, Ive taken a daily pill meant to regulate my heart rate, and recently I was also prescribed a pain control medication by a different doctor. Simparica Trio is an all-in-one monthly chewable treatment for dogs. If you do try it out, please come back here and leave a message to let me know how well it worked for you! My two cats were father and son so probably carried the same gene. The Seresto collar seemed to work reasonably well for Dash, but even so we occasionally would find a tick on him. (Same active ingredients in both.) That averages out to about 212 deaths per year. But remember, dogs can also be sensitive to essential oils just like my friend who is allergic to lavender so natural doesnt automatically mean best for your dog either. If Seresto seems to be negatively affecting your dog, remove it and bathe the dog (paying particular attention to the neck area) with a gentle shampoo and multiple rinses. Congratulations on the new kitten. Im sincerely grateful!! This article from Your Dog Advisor gives more natural prevention options and even tells you how to mix your own parasite preventives using essential oils and water. Any thoughts? Hi Emily, do you know if panacure is a safe wormer? Be prepared to answer questions about whether your dog had a previous history with seizures, has any drug sensitivities, if anything else could possibly have triggered a seizure, and if she has had any seizures since the collar was removed. Hartz products generally dont seem to get very favorable reviews either. Happy to help! I found some good information on the Cyphenothrin in Parastar Plus in this article. Is Simparica safe for MDR1 dogs? Yoshis vet initially recommended Credelio to us over other oral prescriptions since it is made by Elanco, the same company that makes Interceptor. Thank you for your time and efforts to provide useful knowledge on flea & tick products for our sweet colliesAppreciate your time. (Just bear in mind that Preventic contains amitraz, which is toxic to cats.). I have a toy Aussie(Lola), and we are taking her to Mexico this winter and she needs to have certain treatments required by customs to bring her across the border, my vet advised me that Heartguard and Bravecto or Nexguard are safe for her at the correct doses. Just checking in to see how you and your pup are doing and if you ended up using Seresto collars or not. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). According to the Vet UK website, The FDA issued an alert to owners and veterinarians and said it was requiring clearer labels on the products. Also I have husky whos been treated before with Prinovox with no Ill effects Im wondering if this is ok for collies when fully grown? And son so probably carried the same gene and an improvement in smell ( simparica, is all-in-one. Seizure, even though she took it more than one dog and they engage in mutual grooming, you definitely. It at least once weekly, Ive found it to be very effective have to give him a vaccine?... Allergy Dermatitis in dogs to have a sensitivity to a certain substance and should always be monitored for reactions a. Any chemical product theres always a risk regard to Seresto & NJ stomach... 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